• 1. 中國(guó)醫(yī)學(xué)科學(xué)院中國(guó)協(xié)和醫(yī)科大學(xué)北京協(xié)和醫(yī)院普外科(北京100730)2. 中國(guó)醫(yī)學(xué)科學(xué)院中國(guó)協(xié)和醫(yī)科大學(xué)北京協(xié)和醫(yī)院消化內(nèi)科;

引用本文： 李小毅,陳原稼,唐偉松. 生長(zhǎng)抑素治療胃腸道非內(nèi)分泌惡性腫瘤. 中國(guó)普外基礎(chǔ)與臨床雜志, 1999, 6(6): 392-393. doi: 復(fù)制

1. Smith JP, Solomon TE. Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer. Gastroenterology, 1988; 95(6)∶1541.
2. Pinski J, Halmos G, Yano T, et al. Inhibition of growth of MKN45 human gastriccarcinoma xenografts in nude mice by treatment with bombesin/gastrinreleasingpeptide antagonist (RC3095) and somatostatin analogue RC160. Int J Cancer, 1994; 57(4)∶574.
3. Smith JP, Doll D, Croitoru R, et al. Octreoride has no effect on advanced colon cancer. J Clin Gastroenterol, 1994; 18(3)∶245.
4. Qin Y, Cauteren MV, Osteaux M, et al. Inhibitory effect of somatostatin analogue RC160 on the growth of hepatic metastases of colon cancer in rats: a study with magnetic resonance imaging. Cancer Res, 1992; 52(21)∶6025.
5. Reubi JC, Horisberger U, Laissue J. High density of somatostatin receptors in veins surrounding human cancer tissue: role in tumerhost interaction? Int J Cancer, 1994; 56(5)∶681.
6. Reubi JC, Mazzucchelli L, Hennig I, et al. Local upregulation of neuropeptide receptors in host blood vessels around human colorectal cancer. Gastroenterology, 1996; 110(6)∶1719.
7. Davies N, Cooke TG, Jenkins SA. Therapeutic potential of octreotide in the treatment of liver metastases. Anti Cancer Drugs, 1996; 7(Suppl 1)∶23.
8. Buscail L, Delesque N, Esteve JP, et al. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci USA, 1994; 91(6)∶2315.
9. Buscail L, Esteve JP, SaintLaurent N, et al. Inhibition of cell proliferation by the somatostatin analogue RC160 is mediated by somstostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc Natl Acad Sci USA, 1995; 92(5)∶1580.
10. Iftikhar SY, Thomas WM, Rooney PS, et al. Somatostatin receptors in human colorectal cancer. Eur J Surg Oncol, 1992; 18(1)∶27.
11. Miller GV, Farmery SM, Woodhouse LF, et al. Somatostatin binding in normal and malignant human gastrointestinal mucosa. Br J Cancer, 1992; 66(2)∶391.
12. Radulovic SS, Milovanovic SR, Cai RZ, et al. The binding of bombesin and somatostatin and their analogues to human colon cancers. Proc Soc Exp Biol Med, 1992; 200(3)∶394.
13. Miller GV, Preston SR, Woodhouse LF, et al. Somatostatin binding in human gastrointestinal tissues: effect of cations and somatostatin analogues. Gut, 1993; 34(10)∶1351.
14. Buscail L, SaintLaurent N, Chastre E, et al. Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res, 1996; 56(8)∶1823.
15. Laws SA, Gough AC, Evans AA, et al. Somatostatin receptor subtype mRNA expression in human colorectal cancer and normal colonic mucosae. Br J Cancer, 1997; 75(3)∶360.
16. Goldberg RM, Moertel CG, Wieand HS, et al. A ghase Ⅲ evaluation of a somatotatin analogue (Octreotide) in the treatment of patients with asymptomatic advanced colon carcinoma. Cancer, 1995; 76(6)∶961.
17. Stewart GJ, Connor JL, Lawson JA, et al. Octreotide reduces the kinetic index, proliferating cell nuclear antigenmaximum proliferative index, in patients with colorectal cancer. Cancer, 1995; 76(4)∶572.
18. Woltering EA, Watson JC, AlperinLea RC, et al. Somatostatin analogues: angiogenesis inhibitors with novel mechanisms of action. Invest New Drugs, 1997; 15(1)∶77.
  1. 1. Smith JP, Solomon TE. Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer. Gastroenterology, 1988; 95(6)∶1541.
  2. 2. Pinski J, Halmos G, Yano T, et al. Inhibition of growth of MKN45 human gastriccarcinoma xenografts in nude mice by treatment with bombesin/gastrinreleasingpeptide antagonist (RC3095) and somatostatin analogue RC160. Int J Cancer, 1994; 57(4)∶574.
  3. 3. Smith JP, Doll D, Croitoru R, et al. Octreoride has no effect on advanced colon cancer. J Clin Gastroenterol, 1994; 18(3)∶245.
  4. 4. Qin Y, Cauteren MV, Osteaux M, et al. Inhibitory effect of somatostatin analogue RC160 on the growth of hepatic metastases of colon cancer in rats: a study with magnetic resonance imaging. Cancer Res, 1992; 52(21)∶6025.
  5. 5. Reubi JC, Horisberger U, Laissue J. High density of somatostatin receptors in veins surrounding human cancer tissue: role in tumerhost interaction? Int J Cancer, 1994; 56(5)∶681.
  6. 6. Reubi JC, Mazzucchelli L, Hennig I, et al. Local upregulation of neuropeptide receptors in host blood vessels around human colorectal cancer. Gastroenterology, 1996; 110(6)∶1719.
  7. 7. Davies N, Cooke TG, Jenkins SA. Therapeutic potential of octreotide in the treatment of liver metastases. Anti Cancer Drugs, 1996; 7(Suppl 1)∶23.
  8. 8. Buscail L, Delesque N, Esteve JP, et al. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci USA, 1994; 91(6)∶2315.
  9. 9. Buscail L, Esteve JP, SaintLaurent N, et al. Inhibition of cell proliferation by the somatostatin analogue RC160 is mediated by somstostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc Natl Acad Sci USA, 1995; 92(5)∶1580.
  10. 10. Iftikhar SY, Thomas WM, Rooney PS, et al. Somatostatin receptors in human colorectal cancer. Eur J Surg Oncol, 1992; 18(1)∶27.
  11. 11. Miller GV, Farmery SM, Woodhouse LF, et al. Somatostatin binding in normal and malignant human gastrointestinal mucosa. Br J Cancer, 1992; 66(2)∶391.
  12. 12. Radulovic SS, Milovanovic SR, Cai RZ, et al. The binding of bombesin and somatostatin and their analogues to human colon cancers. Proc Soc Exp Biol Med, 1992; 200(3)∶394.
  13. 13. Miller GV, Preston SR, Woodhouse LF, et al. Somatostatin binding in human gastrointestinal tissues: effect of cations and somatostatin analogues. Gut, 1993; 34(10)∶1351.
  14. 14. Buscail L, SaintLaurent N, Chastre E, et al. Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res, 1996; 56(8)∶1823.
  15. 15. Laws SA, Gough AC, Evans AA, et al. Somatostatin receptor subtype mRNA expression in human colorectal cancer and normal colonic mucosae. Br J Cancer, 1997; 75(3)∶360.
  16. 16. Goldberg RM, Moertel CG, Wieand HS, et al. A ghase Ⅲ evaluation of a somatotatin analogue (Octreotide) in the treatment of patients with asymptomatic advanced colon carcinoma. Cancer, 1995; 76(6)∶961.
  17. 17. Stewart GJ, Connor JL, Lawson JA, et al. Octreotide reduces the kinetic index, proliferating cell nuclear antigenmaximum proliferative index, in patients with colorectal cancer. Cancer, 1995; 76(4)∶572.
  18. 18. Woltering EA, Watson JC, AlperinLea RC, et al. Somatostatin analogues: angiogenesis inhibitors with novel mechanisms of action. Invest New Drugs, 1997; 15(1)∶77.