• 1.北京協(xié)和醫(yī)院外科(北京100730)2.北京東單兒童醫(yī)院;

19只貓隨機分成A組和B組。A組7只接受全胰腺點狀注射酒精,B組12只經(jīng)主胰管插管注射酒精,并將導管留在主胰管內造成主胰管部分梗阻,再全胰腺點狀注射酒精。結果:術后全部實驗貓均發(fā)生急性壞死性胰腺炎(ANP)。A組2只貓(28.6%)在48小時內死亡,5只貓術后6周胰腺組織形態(tài)和外分泌功能基本恢復正常。B組死亡4只(占33.3%),其中3只在術后48小時內死亡,另1只在術后2周死亡。其余8只貓術后15周全部發(fā)展成慢性胰腺炎。由此提示單純胰腺壞死可在致病因去除后得到恢復;如果致病因繼續(xù)起作用,可造成組織學和功能方面的不可逆損害,最終可能發(fā)展成慢性胰腺炎。

引用本文: 趙華,屠建,鐘守先,唐偉松. 貓胰腺壞死后的轉歸初探. 中國普外基礎與臨床雜志, 1996, 3(1): 1-3. doi: 復制

1. Ehrhardt-Schmelzer S,Otto J,Schlaeger R,et al.Fecal chymotrypsin for investigation of exocrine pancreatic function:a comparison of two newly developed tests with the titrimeteric method.Gastroenterol,1984;22:647.
2. Lankisch PG,Brauneis J,Otto J,et al.Pancreolauryl and NBT-PABA tests.Gastroenterol,1986;90:350.
3. Van De Kamer JH,Ten Bokkel Huinink H,Weyers HA.Rapid method for the determination of fat in the feces.J Biol Chem,1949;177:347.
4. Beger HG.Surgical management of necrotizing pancreatitis.Surg Clin North Am,1989;69:529.
5. Bradley EL Ⅲ,Allen K.A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis.Am J Surg,1991;161:l0.
6. Warshaw AL.A guide to pancreatitis.Comp Ther,l980;6:49.
7. Fenton-Lee D,Imrie CW.Pancreatic necrosis:assessment of outcome related to quality of life and cost of management.Br J Surg,1993;80(12):1579.
8. Mitchell CJ,Playforth MJ,Mcmahon MJ.Functional recovery of the exocrine pancreas after acutepancreatitis.Scand J Gastroenterol,1983;18:5.
9. Sarles H.Proposal adopted unanimously by thepartocipants of the symposium on pancreatitis at marseilles.Gastroentecol,1965;7:7.
10. Klopple G,Maillet B.The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis.Virchows Archiv A Pothol Anat,l992;420:1.
  1. 1. Ehrhardt-Schmelzer S,Otto J,Schlaeger R,et al.Fecal chymotrypsin for investigation of exocrine pancreatic function:a comparison of two newly developed tests with the titrimeteric method.Gastroenterol,1984;22:647.
  2. 2. Lankisch PG,Brauneis J,Otto J,et al.Pancreolauryl and NBT-PABA tests.Gastroenterol,1986;90:350.
  3. 3. Van De Kamer JH,Ten Bokkel Huinink H,Weyers HA.Rapid method for the determination of fat in the feces.J Biol Chem,1949;177:347.
  4. 4. Beger HG.Surgical management of necrotizing pancreatitis.Surg Clin North Am,1989;69:529.
  5. 5. Bradley EL Ⅲ,Allen K.A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis.Am J Surg,1991;161:l0.
  6. 6. Warshaw AL.A guide to pancreatitis.Comp Ther,l980;6:49.
  7. 7. Fenton-Lee D,Imrie CW.Pancreatic necrosis:assessment of outcome related to quality of life and cost of management.Br J Surg,1993;80(12):1579.
  8. 8. Mitchell CJ,Playforth MJ,Mcmahon MJ.Functional recovery of the exocrine pancreas after acutepancreatitis.Scand J Gastroenterol,1983;18:5.
  9. 9. Sarles H.Proposal adopted unanimously by thepartocipants of the symposium on pancreatitis at marseilles.Gastroentecol,1965;7:7.
  10. 10. Klopple G,Maillet B.The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis.Virchows Archiv A Pothol Anat,l992;420:1.