目的:探討更為安全、有效的靜脈補鉀治療低鉀型周期性麻痹的方法。方法:收集本院住院低鉀型周期性麻痹患者,應用半隨機法分為治療組和對照組進行臨床對照研究。治療組將氯化鉀加入5%甘露醇靜脈補鉀,對照組常規(guī)補鉀,監(jiān)測血鉀及肌力的恢復情況。結果:治療組療效明顯,優(yōu)于對照組(P lt;0.05)。結論:將氯化鉀加入5%甘露醇治療低鉀型周期性麻痹療效好,安全可行。
引用本文: 黃艷,蒲飛,周紅雨. 氯化鉀加入甘露醇治療低鉀型周期性麻痹42例療效觀察. 華西醫(yī)學, 2009, 24(2): 407-408. doi: 復制
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- 2. Cannon S C.Pathomechanisms in channelopathies of skeletal muscle and brain[J].Annu Rev Neurosci,2006,29:387-415..
- 3. Arie F.Struyk,Stephen C.Cannon.A Na+ channel mutation linked to hypokalemic periodic paralysis exposes a protonselective gating pore[J].J Gen Physiol,2007,130(1):11-20..
- 4. Lin SH, Lin YF, Halperin ML.Hypokalaemia and paralysis[J].QJM,2001,94(3):133-139..
- 5. Kung AW.Clinical review: Thyrotoxic periodic paralysis: a diagnostic challenge[J]. J Clin Endocrinol Metab,2006,91(7):2490-2495..
- 6. Levitt JO.Practical aspects in the management of hypokalemic periodic paralysis[J].J Transl Med,2008,6:18..