• 四川大學(xué)華西醫(yī)院感染性疾病中心,四川成都 610041;

目的:探討激素及免疫抑制劑導(dǎo)致乙肝病毒再激活所致的肝損害的危害性及治療效果,指導(dǎo)臨床治療。方法:總結(jié)本院近2年收治的7例慢性乙肝病毒感染者在使用激素及免疫抑制劑致肝炎再激活并加重患者的臨床資料進(jìn)行分析。結(jié)果:慢性乙肝病毒感染者因各種原因使用激素及免疫抑制劑所導(dǎo)致的慢性乙肝的復(fù)發(fā)加重,病情發(fā)展迅速,病死率高。結(jié)論:抗乙肝病毒治療是預(yù)防肝病復(fù)發(fā)并惡化的關(guān)鍵,在激素或免疫抑制劑治療前和治療中都應(yīng)使乙肝病毒降至盡可能低的水平。

引用本文: 冉靜,馮萍. 糖皮質(zhì)激素及免疫抑制劑致慢性乙肝復(fù)發(fā)和加重的7例臨床分析. 華西醫(yī)學(xué), 2009, 24(2): 419-421. doi: 復(fù)制

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  2. 2. Rossi G,Pelizzari A,Motta M,et al.Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy[J].Br J Haematol,2001,115(1):58-62..
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  4. 4. Benner KG,Loe RG,Keeffe EB,et al.Fibrosing cytolytic liver failure secondary to recurrent hepatitis B after livertransplantation[J].Gastroenterology,1992,103(4):1307-1312..
  5. 5. Lee WC,Wu MJ,Cheng CH,et al.Lamivudine is effective for the treatment of reactivation of hepatitis B virus and fulminant hepatic failure in renal transplant recipients[J].Am J Kidney Dis,2001,38(5):1074-81..
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