• 成都軍區(qū)總醫(yī)院1PET/CT中心;2放療科,四川成都 610083;

目的:探討18F-FDG PET/CT在頭頸部腫瘤的臨床應(yīng)用價值。方法:58例頭頸部惡性腫瘤病例,男37例,女21例,年齡21~78歲。其中:牙齦癌3例,上頜竇癌2例,舌癌2例,腮腺癌1例,鼻咽癌24例,喉癌8例,甲狀腺癌4例,原發(fā)灶不明的頸部淋巴結(jié)轉(zhuǎn)移瘤14例。使用18F-FDG行全身PET/CT掃描,依據(jù)PET圖像、CT圖像和PET/CT融合圖像及標(biāo)準(zhǔn)化攝取值(SUV)進行綜合評價。結(jié)果:29例放療患者中的11例擬行根治性放療的患者,有4例改行姑息性放療,8例重新勾畫了放療靶區(qū)及調(diào)整了放療劑量,3例改行其它治療;15例進行了放療后的療效評估;14例原發(fā)灶不明的頸部淋巴結(jié)轉(zhuǎn)移瘤8例找到了原發(fā)灶。結(jié)論:PET/CT可以對頭頸部惡性腫瘤進行準(zhǔn)確的臨床分期,精確勾畫放療的生物靶區(qū),準(zhǔn)確而快捷地確定腫瘤復(fù)發(fā)的位置與侵犯范圍,在頸部不明原發(fā)灶轉(zhuǎn)移瘤的應(yīng)用中具有簡便、快捷、無創(chuàng)和靈敏等臨床特點。

引用本文： 周克,駱建華,陳治明,吳平,楊春敏,楊勤. 18F-FDG PET/CT在頭頸部腫瘤中的應(yīng)用. 華西醫(yī)學(xué), 2009, 24(6): 1490-1492. doi: 復(fù)制

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  2. 2. SHODER H, YEUNG H W D, GONEN M, et al. Head and neck cancer: clinical usefulness and accuracy of PET/CT image fusion[J]. Radiology,2004,231:65-72.
  3. 3. DIZENDORF E V, BOUMER B G, VON SCHULTHESS G K, et al. Impact of wholebody 18FFDG PET on staging and managing patients for radiation therapy[J]. J Nucl Med,2002,44:24-29.
  4. 4. CIERNIK I F, DIZERDORF E, BOUMENT B G, et al. Radiation treatment planning with on integrated position emission and computed tomography (PET/CT): a feasibility study[J]. Int J Radiat Oncol Biol Phys,2003,57:853-863.
  5. 5. DIZENDORF E. Impact biologic target volumes in radiation treatment planning[J]. J Nucl Med,2002,(435):A-118.
  6. 6. GREVEN K M, WILLIAMS D W, KEYES J W, et al. Distinguishing tumor recurrence from irradiation sequel as with positron emission tomography in patients treated for larynx cancer[J]. Int J Radiat Oncol Biolphys,1994,29:841-845.
  7. 7. NARESH K N. Do metastatic tumours from an unknown primary angiugemic incompetence of the tumour at primary site? A hypotheses[J]. Med Hypotheses,2002,3:357.
  8. 8. ALBERINI J L， BELHOCINE T, HUSTINX R, et al. Whole body positron emission tomography using fluoride OXY glucose in patients with metastases of unknown tunours (CPU syndrome)[J]. Nucl Med Commun,2003,10:1081.
  9. 9. DELGADO BULTON RC, FEMADEZ C, CNORZAL MATE A, et al. Meta analysis of the performance of 18FFDG PET in primary tumor detection in unknow primary tumors[J]. J Nucl Med,2000,5:816.